Cite this article as:

Amelin V. G., Amelin A. I. Rapid Determination of Tetracyclines in Milk by the Method of Mass Spectrometry High Resolution. Izvestiya of Saratov University. Chemistry. Biology. Ecology, 2015, vol. 15, iss. 2, pp. 8-13. DOI: https://doi.org/10.18500/1816-9775-2015-15-2-8-13

This is an open access article distributed under the terms of Creative Commons Attribution 4.0 International License (CC-BY 4.0).
Heading: 
Chemistry
UDC: 
636.085.3:577.18:543
Language: 
Russian

Rapid Determination of Tetracyclines in Milk by the Method of Mass Spectrometry High Resolution

Authors: 
Amelin V. G., Vladimir State University. Department of Chemistry, 600000, Vladimir, Gorky str., 87, amelinvg@mail.ru
Amelin A. I., Vladimir State University, 600000, Vladimir, Gor'kogo str., 87, amelinvg@mail.ru
Abstract

The method of determination of tetracycline antibiotics (tetracycline, chlortetracycline, oxytetracycline, doxycycline) in the milk of methods HPLC-MS/MS/MS and HPLC-QTOF-MS, with a simple and rapid sample preparation. The ranges defined concentrations of tetracyclines in milk sample of 1 g was 1–200 μg/kg. Relative standard deviation of the results of the analysis does not exceed 7%. The analysis duration 30–40 minutes.

Key words: 
tetracycline, milk, high resolution mass spectrometry, HPLC-MS/MS/MS, HPLC-QTOF-MS
DOI: 
https://doi.org/10.18500/1816-9775-2015-15-2-8-13
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Full text (in Russian): 
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