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Zaitseva N. V., Ulanova Т. S., Karnazhitskaya Т. D., Zavernenkova Е. О. Study of Correlation between Growth Rate of Children and Monophtalate Concentrations in Urine. Izvestiya of Saratov University. Chemistry. Biology. Ecology, 2017, vol. 17, iss. 1, pp. 62-66. DOI: https://doi.org/10.18500/1816-9775-2017-17-1-62-66


This is an open access article distributed under the terms of Creative Commons Attribution 4.0 International License (CC-BY 4.0).
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Study of Correlation between Growth Rate of Children and Monophtalate Concentrations in Urine

Abstract

The study presents the results of determining of phthalate metabolites in urine of pre-school and primary school children by HPLC/MS. The correlation between growth rate of children and the concentration of phthalate metabolites in their urine was examined. The detected range of phthalate metabolite concentrations (mono-methyl phthalate, mono-butyl phthalate, mono-ethylhexyl phthalate) in urine of children was 0.0004–0.012 mg/dm3. The analysis of dependencies «urinary concentrations of phthalate metabolites and children growth rate» has revealed statistically significant inversely proportional dependence of the growth rate of the 7 years old boys on the urinary concentration of mono-methyl phthalate (R2=0.38; р<0.05).

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