Cite this article as:

Danilina T. G., Smirnova T. D., Bryshkina A. D., Levina N. A., Nevryueva N. V. The Effect of Surfactant Micelles on the Fluorescent Properties of a Complex of Yttrium with Levofloxacin. Izvestiya of Saratov University. Chemistry. Biology. Ecology, 2019, vol. 19, iss. 4, pp. 372-378. DOI: https://doi.org/10.18500/1816-9775-2019-19-4-372-378

This is an open access article distributed under the terms of Creative Commons Attribution 4.0 International License (CC-BY 4.0).
Heading: 
Chemistry
UDC: 
543.426
Language: 
Russian

The Effect of Surfactant Micelles on the Fluorescent Properties of a Complex of Yttrium with Levofloxacin

Authors: 
Danilina Tatiana Grigorievna, Saratov State University , 83, Astrakhanskaya str., Saratov, 410012, Russia , tanushechka900@mail.ru
Smirnova Tatiana D., Saratov State University, 83, Astrakhanskaya St., Saratov, 410012, Russia, smirnovatd@mail.ru
Bryshkina Anastasia D. , Saratov State University , 83, Astrakhanskaya str., Saratov, 410012, Russia , a.brushkina@yandex.ru
Levina Natalya A. , Saratov State University , 83, Astrakhanskaya str., Saratov, 410012, Russia , levina3009@mail.ru
Nevryueva Natalia Vladimirovna, Saratov State Medical University, 112, Bolshaya Kazachya Str., Saratov, 410010, Russia, natasha.k.83@mail.ru
Abstract

The effect of complexation with yttrium ions and micellar media of surfactants on the fluorescent properties of levofloxacin was studied. The luminescence of levofloxacin depends on the acidity of the medium Т. Г. Данилина и др. Влияние мицелл поверхностно-активных веществ 378 Научный отдел Изв. Сарат. ун-та. Нов. сер. Сер. Химия. Биология. Экология. 2019. Т. 19, вып. 4 and is maximum in an acidic medium. It was shown that complexation with yttrium ions promotes the growth of the intrinsic fluorescence of levofloxacin by a factor of 2. In a weakly alkaline medium, complex formation is accompanied by an increase in intensity of 1.3 times and a bathochromic shift of the absorption band in the spectra of the biologically active ligand. Complexation in micellar media is accompanied by an additional increase in the emission signal by 3 times. The concentration ranges of levofloxacin in which there is a linear dependence on the luminescence intensity of the studied systems are established. The optimal conditions for the maximum fluorescence signal of levofloxacin in aqueous and micellar media of surfactants are found.

Key words: 
fluorescence, levofloxacin, complexation with yttrium ions, micellar surfactant media
DOI: 
https://doi.org/10.18500/1816-9775-2019-19-4-372-378
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Full text (in Russian): 
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