Cite this article as:

Nevryueva N. V., Smirnova T. D. Method of Determination of Ciprofloxacin HPLC Using Organized Mediain Pharmaceuticals. Izvestiya of Saratov University. Chemistry. Biology. Ecology, 2015, vol. 15, iss. 1, pp. 5-9. DOI: https://doi.org/10.18500/1816-9775-2015-15-1-5-9

This is an open access article distributed under the terms of Creative Commons Attribution 4.0 International License (CC-BY 4.0).
Heading: 
Chemistry
UDC: 
543.544.5.068.7
Language: 
Russian

Method of Determination of Ciprofloxacin HPLC Using Organized Mediain Pharmaceuticals

Authors: 
Nevryueva Natalia Vladimirovna, Saratov State Medical University, 112, Bolshaya Kazachya Str., Saratov, 410010, Russia, natasha.k.83@mail.ru
Smirnova Tatiana D., Saratov State University, 83, Astrakhanskaya St., Saratov, 410012, Russia, smirnovatd@mail.ru
Abstract

It is shown that in the analysis of medicines fluoroquinolone by reversed-phase HPLC with fluorimetric detection modification mobile phase γ-cyclodextrin leads to a decrease in the detection limit of antibiotics to 8 times. The possibility of determination of cipro- floxacin in the presence of tetracycline and quinolone derivative series. The proposed method is tested in the analysis of pharmaceutical preparations containing ciprofloxacin.

Key words: 
high performance liquid chromatography, fluoroquinolones, fluorescence, organized environment
DOI: 
https://doi.org/10.18500/1816-9775-2015-15-1-5-9
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