Cefotaxime

Transport Properties of Membranes on the Basis of Tetradecylammonium Associates with Complex Compounds Silver(I)-сefotaxime

Authors: Kulapina E. G., Tyutlikova M. S., Mursalov R. K.

Transport properties of the plasticized polyvinylchloride membranes on the basis of tetradecylammonium associates with complex connections silver (I) – cefotaxime in the conditions of a diffusive mass transfer and a direct current are investigated. With variation of concentration of electrode active substances (0.5; 1; 2; 3%), the external solutions contacting with membranes (10-2–10-7 M). It is established that resistance of membranes depends on the content of electrode active substances (EAS) and concentration of perimembrane solutions of a cefotaxime.

The Solid-state and Planar Sensors for the Determination of Cefotaxime in Aqueous and Biological Fluids

Authors: Kulapina E. G., Tyutlikova M. S.

Cefotaxime is a cefalosporin antibiotic possessing a high efficiency at curing severe bacterial infections. For the determination of cephalosporin antibiotics in different objects, spectroscopic, chromatographic, electrochemical methods, immunoassay, etc. are used, which demand for expensive devices and organic solvents. Potentiometric sensors let one expressively detect cefalosporin antibiotics in small samples without previous sample preparation.

Research of a State of Some the Cephalosporin Antibiotics in Water Environments by Spectrophotometry

Authors: Kulapina O. I., Karenko V. A., Kulapina E. G.

An express authenticity estimation of some cephalosporin antibiotics of II and III generations are developed by spectrophotometry. An identity of drugs such as cefotaxime (Russia) and claforan (France), cefuroxime (Russia) and cefuroxime axetil (England) is shown.