UV

Some aspects of antimicrobial photodynamic eff ects

Authors: Tuchina E. S.

Antimicrobial phototherapy is an alternative method for combating clinically signifi cant microorganisms associated with lesions of the skin, mucous membranes of the oral cavity, respiratory, gastrointestinal and urogenital tracts. The method uses non-toxic dyes called photosensitizers, molecules that can be excited by harmless visible light to form reactive oxygen species. Numerous studies of the method in vitro and in vivo have demonstrated the destruction of microorganisms or a signifi cant reduction in their number.

Antimicrobial Photodynamic Effects Using Coatings Based on Metal Nanoparticles (Ag, Au)

Authors: Tuchina E. S., Gvozdev G. A., Kosobudskiy I. D., Shih W., Tuchin V. V.

The combined effect of coatings based on nanoparticles of metals Ag, Au, ultraviolet (365 nm, UVR) and infrared (808 nm, IRR) radiation on Staphylococcus aureus 209 P was studied. Decrease in numbers was shown by 2% in the case of silver coatings and by 8% in the case of gold coatings after 1 h incubation. However, exposure of the IRR to bacterial suspensions caused the death of 43% of the population after 5 min, 86% of the population after 30 min.