Cite this article as:

Tuchina E. S. Some aspects of antimicrobial photodynamic eff ects. Izvestiya of Saratov University. Chemistry. Biology. Ecology, 2022, vol. 22, iss. 1, pp. 33-46. DOI: https://doi.org/10.18500/1816-9775-2022-22-1-33-46

This is an open access article distributed under the terms of Creative Commons Attribution 4.0 International License (CC-BY 4.0).
Heading: 
Biology
UDC: 
577.344.3:579.61:666.1.056
Language: 
Russian

Some aspects of antimicrobial photodynamic eff ects

Authors: 
Tuchina Elena S., SSU. Department of Biology. Department of Biochemistry and Biophysics, 410012, Saratov, ul. Astrakhanskaya, 83, building. 5, Faculty of Biology, kliany@rambler.ru
Тип статьи для РИНЦ: 
RAR научная статья
Abstract

Antimicrobial phototherapy is an alternative method for combating clinically signifi cant microorganisms associated with lesions of the skin, mucous membranes of the oral cavity, respiratory, gastrointestinal and urogenital tracts. The method uses non-toxic dyes called photosensitizers, molecules that can be excited by harmless visible light to form reactive oxygen species. Numerous studies of the method in vitro and in vivo have demonstrated the destruction of microorganisms or a signifi cant reduction in their number. Reactive oxygen species are produced upon photoactivation and attack targets such as proteins, lipids, and nucleic acids present inside microbial cells. This review is intended to highlight current data on antimicrobial photoexposure.

Key words: 
photodynamic therapy, photodynamic action, photosensitizers, porphyrins, UV, microorganisms
DOI: 
https://doi.org/10.18500/1816-9775-2022-22-1-33-46
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